Woman uses finger to hide fever blister on lip; male healthcare provider takes a woman's blood pressure measurement with BP cuff; online doctor smiles at telehealth patient from mobile phone

Cold sores (oral herpes)

Prescription medication can shorten or prevent cold sore outbreaks by fighting the virus that causes them.

Quickly treat cold sores with 24/7 virtual care

$29
/message visit
$49
/video visit
*Messaging is not available in some states
• Self-pay visits - insurance not accepted or needed, FSA/HSA eligible
• Fast care - no appointment necessary
• Prime not required
• Your health data is secure and protected by our practices and by law
How it works
1. Choose a condition you need help with, answer some questions, and connect with a provider through message or video
2. Pick up any prescribed medication at a pharmacy of your choice or have it delivered
3. You have 14 days to follow up with the provider on any questions you may have
Explore ways to get care

Membership

Best for
• Booking same/next-day appointments* at offices near you with the app
• Booking primary care visits* for mental health, preventive care, chronic conditions, and more in states where we have offices
• 24/7 on-demand virtual care for quick treatment of common conditions, anywhere in the U.S. at no extra cost.
• Major insurance accepted for in-office and remote visits*

Pay-per-visit

Best for
• Quick treatment of common conditions
• Care by message or video**
• Self-pay visits – no insurance accepted or needed
• FSA/HSA eligible
*These appointments will be billed to you or your insurance
Membership
Pay-per-visit
Services
Common conditions
checkmark in a teal circle
checkmark in a teal circle
Select Rx renewal
checkmark in a teal circle
checkmark in a teal circle
Access
How to access care
One Medical app
Onemedical.com
Amazon.com
Schedule visits, in-office or remote*
checkmark in a teal circle
white x in a grey circle
Message with your care team
On demand
14-day
24/7 on-demand virtual care via message** and video
checkmark in a teal circle
checkmark in a teal circle
Payment
Membership fee
$9/mo or $99/yr for Prime members
$199/yr for non-Prime members
No membership fee
Prime membership required
white x in a grey circle
white x in a grey circle
Cost for on-demand virtual care
Included in the membership
$29 or $49
Insurance
Accepted for scheduled visits
Not accepted
FSA/HSA eligible
Accepted for scheduled visits
checkmark in a teal circle
**Messaging via Pay-per-visit is only available in 34 states
Learn more details via our FAQs

Get help for cold sores and other health concerns

$9

/month

$99

/year
45% savings
with Prime
calendar icon
Book same/next day in-office appointments via the app
Scheduled visits (in-office/remote) billed to your insurance separately (cost sharing applies). One Medical accepts most insurance.
For $9/month, you can
• Book same/next day appointments at offices near you with the One Medical app
• Get 24/7 on-demand virtual care via video or messaging
• Send and receive secure messages with your care team
• Easily request prescription refills and renewals

Quickly treat cold sores with 24/7 virtual care

$29
/message visit
$49
/video visit
*Messaging is not available in some states
• Self-pay visits - insurance not accepted or needed, FSA/HSA eligible
• Fast care - no appointment necessary
• Prime not required
• Your health data is secure and protected by our practices and by law
How it works
1. Choose a condition you need help with, answer some questions, and connect with a provider through message or video
2. Pick up any prescribed medication at a pharmacy of your choice or have it delivered
3. You have 14 days to follow up with the provider on any questions you may have
Explore ways to get care

Membership

Best for
• Booking same/next-day appointments* at offices near you with the app
• Booking primary care visits* for mental health, preventive care, chronic conditions, and more in states where we have offices
• 24/7 on-demand virtual care for quick treatment of common conditions, anywhere in the U.S. at no extra cost.
• Major insurance accepted for in-office and remote visits*

Pay-per-visit

Best for
• Quick treatment of common conditions
• Care by message or video**
• Self-pay visits – no insurance accepted or needed
• FSA/HSA eligible
*These appointments will be billed to you or your insurance
Membership
Pay-per-visit
Services
Common conditions
checkmark in a teal circle
checkmark in a teal circle
Select Rx renewal
checkmark in a teal circle
checkmark in a teal circle
Access
How to access care
One Medical app
Onemedical.com
Amazon.com
Schedule visits, in-office or remote*
checkmark in a teal circle
white x in a grey circle
Message with your care team
On demand
14-day
24/7 on-demand virtual care via message** and video
checkmark in a teal circle
checkmark in a teal circle
Payment
Membership fee
$9/mo or $99/yr for Prime members
$199/yr for non-Prime members
No membership fee
Prime membership required
white x in a grey circle
white x in a grey circle
Cost for on-demand virtual care
Included in the membership
$29 or $49
Insurance
Accepted for scheduled visits
Not accepted
FSA/HSA eligible
Accepted for scheduled visits
checkmark in a teal circle
**Messaging via Pay-per-visit is only available in 34 states
Learn more details via our FAQs

Quickly treat cold sores with 24/7 virtual care

$29
/message visit
$49
/video visit
*Messaging is not available in some states
• Self-pay visits - insurance not accepted or needed, FSA/HSA eligible
• Fast care - no appointment necessary
• Prime not required
• Your health data is secure and protected by our practices and by law
How it works
1. Choose a condition you need help with, answer some questions, and connect with a provider through message or video
2. Pick up any prescribed medication at a pharmacy of your choice or have it delivered
3. You have 14 days to follow up with the provider on any questions you may have

Get help for cold sores and other health concerns

$9

/month

$99

/year
45% savings
with Prime
This benefit is exclusively for Prime members
calendar icon
Book same/next day in-office appointments via the app
Scheduled visits (in-office/remote) billed to your insurance separately (cost sharing applies). One Medical accepts most insurance.
For $9/month, you can
• Book same/next day appointments at offices near you with the One Medical app
• Get 24/7 on-demand virtual care via video or messaging
• Send and receive secure messages with your care team
• Easily request prescription refills and renewals
Amazon Clinic is now Amazon One Medical
Two female friends walk down urban street, chatting with shopping bags

What causes cold sores?

Cold sores, also known as fever blisters, are caused by a herpes simplex virus (usually HSV-1). Once you’re infected with the virus, it stays in your neurons and can be reactivated throughout your life. Most people with oral herpes are infected in childhood.

When is the best time to start cold sore treatment?

Antiviral cold sore medications work best when taken within 3 days of symptoms starting. When taken at the start of an outbreak, these medications can reduce the severity of your symptoms, shorten your outbreak, and lower your risk of spreading cold sores.

Antiviral medications like valacyclovir (Valtrex) can also be taken long-term to suppress the herpes virus (HSV) in people who experience 6 or more cold sore outbreaks in a year.

Is Pay-per-visit right for me?

checkmark in a teal circle
You're 18-64
checkmark in a teal circle
You’ve been diagnosed with oral herpes (cold sores)
checkmark in a teal circle
You don’t have kidney problems, a seizure disorder, or an immunocompromising condition
checkmark in a teal circle
You're not pregnant

Commonly prescribed cold sore medications

Your Amazon One Medical provider will determine which (if any) oral herpes treatment is medically appropriate for you based on your symptoms and health history. If you're prescribed medication, pick it up at a pharmacy of your choice. Choose Amazon Pharmacy for free delivery and transparent Prime pricing. The cost of your prescribed medication may be covered by health insurance.
Pill bottle icon
Antiviral medications
• Acyclovir (Zovirax)
• Famciclovir (Famvir)
• Valacyclovir (Valtrex)
Online doctor smiles at telehealth patient from mobile phone

Not sure where to start?

For a one-time fee of $49, a One Medical provider can diagnose and treat common health complaints, renew prescriptions, and answer your questions in real time. Restrictions apply.

Frequently asked questions

About Amazon One Medical

What are my telehealth options for this condition?
Amazon One Medical offers multiple ways to get care from the comfort of your own home.

If you're a One Medical member and you live in a state where One Medical has offices, you can schedule Remote Visits with One Medical providers, which are billable to you or your health insurance. As a member, you can also get 24/7 on-demand virtual care with Treat Me Now or Urgent Video Chat via the One Medical app at no extra cost, no matter where you live in the United States.

If you're not a One Medical member, you can start a one-time virtual visit with Pay-per-visit. Pay-per-visit offers two types of telehealth for Amazon customers: video visits and message-only visits. Video visits are available for $49 in all 50 states and D.C. Message-only visits are currently available for $29 in 34 states.

To see your Pay-per-visit options, first choose your state.
Can I use my health insurance for Pay-per-visit?
Amazon One Medical doesn't accept health insurance for Pay-per-visit care. You can submit a claim to your insurance provider for reimbursement, but we can’t guarantee they’ll reimburse you for your one-time virtual visit.

If you normally use insurance to pay for your medications, you can do that with medications prescribed through all Amazon One Medical services. Amazon Pharmacy accepts most insurance plans. For other pharmacies, please talk with your pharmacy directly about insurance coverage. The cost of medication isn’t included in the cost of your visit.
What happens if my provider can't diagnose or treat my health issue through Amazon One Medical Pay-per-visit?
If your provider can’t diagnose or treat your health issue through Pay-per-visit, they may recommend that you see a primary care provider or a specialist for in-person care. If that happens, you won't be charged.
Can I communicate with a provider after I get my Pay-per-visit treatment plan?
Yes. When you use Pay-per-visit, you can message with One Medical providers within your personal dashboard for an additional 2 weeks (14 days) at no extra cost. This complimentary communication window allows you time to:
Ask follow-up questions about any prescriptions or over-the-counter medications in your treatment plan

• Connect with a provider if you think your treatment needs to be adjusted

• Tell a provider if you're experiencing side effects from your medication

• Tell a provider if there's an issue getting your prescription from the pharmacy

• Let the One Medical care team know that you're feeling better
Your secure, HIPAA-compliant message will be received by the first available provider, who will be able to review your visit’s treatment plan and any follow-up correspondence. If you still need treatment adjustments or have questions after the 14-day communication window, you'll need to start a new visit.
What if I want to refill my medication?
If your provider didn't include refills with a prescription when they sent your treatment plan through Pay-per-visit, you'll need to start a new one-time virtual visit to request another prescription.

There are many reasons why a provider may decide that prescription refills aren't medically appropriate. For example, they may want to assess how well a medication is working and whether or not it needs to be adjusted before you continue with the same treatment.
How does Amazon One Medical protect my health information?
Amazon One Medical protects customers’ protected health information (PHI) with stringent, Health Insurance Portability and Accountability Act (HIPAA)-compliant privacy and security practices to keep information safe and secure.

We’re committed to building an infrastructure that fosters and promotes a culture of customer privacy and a strong commitment to safeguarding health information. We maintain administrative, physical, and technical safeguards to protect customer information. This includes conducting rigorous security reviews and testing during product development, using encryption to protect data, and providing features like two-step verification to help customers protect their accounts.

Amazon does not sell customers’ personal information, including PHI.

About cold sores and the herpes virus

How do I prevent cold sore outbreaks naturally?
Because recurring cold sores are caused by the reactivation of a virus, you can help prevent outbreaks by taking care of your immune system. Getting the recommended amounts of sleep and exercise, eating healthy food, and keeping your stress levels down can help defend your body against all kinds of illness, including HSV-1.

You can also help prevent cold sores by protecting yourself from too much sun exposure, and by keeping your lips moisturized when you visit the dentist. Both UV light and dental procedures can cause subtle lip damage known to reactivate HSV-1.
Can I give herpes to someone else even if I don't have symptoms?
Yes, you can infect someone with oral herpes or genital herpes even when you're not having symptoms like fever blisters or genital lesions. But you're more likely to spread the virus if you have active sores or scabs.
Can I request treatment for future cold sore outbreaks?
Yes, you can request a cold sore prescription to treat future outbreaks through Amazon One Medical. Then you'll have your medication on hand to take at the first sign of oral herpes. When taken within 72 hours of symptoms starting, antiviral medications are clinically proven to help fever blisters heal faster.
Clinical sources
1. Corey, L., & Spear, P. G. (1986). Infections with herpes simplex viruses (1). The New England journal of medicine, 314(11), 686–691. Retrieved from https://www.nejm.org/doi/10.1056/NEJM198603133141105
2. World Health Organization. (2023). Herpes simplex virus. Who.int; World Health Organization: WHO. https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus