EpiPen injected into thigh; male healthcare provider takes a woman's blood pressure measurement with BP cuff; online doctor smiles at telehealth patient from mobile phone

Epinephrine auto-injectors (EpiPens)

Need to renew your EpiPen prescription?
Get care from Amazon One Medical with a one-time virtual visit or become a member to easily book an in-office appointment.
Explore ways to get care


Best for
• Booking same/next-day appointments* at offices near you with the app
• Booking primary care visits* for mental health, preventive care, chronic conditions, and more in states where we have offices
• 24/7 on-demand virtual care for quick treatment of common conditions, anywhere in the U.S. at no extra cost.
• Major insurance accepted for in-office and remote visits*


Best for
• Quick treatment of common conditions
• Care by message or video**
• Self-pay visits – no insurance accepted or needed
• FSA/HSA eligible
Common conditions
checkmark in a teal circle
checkmark in a teal circle
Select Rx renewal
checkmark in a teal circle
checkmark in a teal circle
How to access care
One Medical app
Schedule visits, in-office or remote*
checkmark in a teal circle
white x in a grey circle
Message with your care team
On demand
24/7 on-demand virtual care via message** and video
checkmark in a teal circle
checkmark in a teal circle
Membership fee
$9/mo or $99/yr for Prime members
$199/yr for non-Prime members
No membership fee
Prime membership required
white x in a grey circle
white x in a grey circle
Cost for on-demand virtual care
Included in the membership
$29 or $49
Accepted for scheduled visits
Not accepted
FSA/HSA eligible
Accepted for scheduled visits
checkmark in a teal circle
*These appointments will be billed to you or your insurance
**Messaging via Pay-per-visit is only available in 34 states
Learn more details via our FAQs

Get help for EpiPen refills and other health concerns




45% savings
with Prime
There’s no nearby One Medical office based on your address
But you can still access 24/7 on-demand care with the One Medical app
calendar icon
Book same/next day in-office appointments via the app
Scheduled visits (in-office/remote) billed to your insurance separately (cost sharing applies). One Medical accepts most insurance.
For $9/month, you can
• Book same/next day appointments at offices near you with the One Medical app
• Get 24/7 on-demand virtual care via video or messaging
• Send and receive secure messages with your care team
• Easily request prescription refills and renewals

Quickly request EpiPens with 24/7 virtual care

/message visit
/video visit
*Messaging is not available in some states
• Self-pay visits - insurance not accepted or needed, FSA/HSA eligible
• Fast care - no appointment necessary
• Prime not required
• Your health data is secure and protected by our practices and by law
How it works
1. Choose a condition you need help with, answer some questions, and connect with a provider through message or video
2. Pick up any prescribed medication at a pharmacy of your choice or have it delivered
3. You have 14 days to follow up with the provider on any questions you may have
Amazon Clinic is now Amazon One Medical
Male healthcare provider with bald head speaks to young male patient in clinical exam room

Who needs an EpiPen?

EpiPens are prescribed to people who are at risk of having a severe and potentially fatal allergic reaction called anaphylaxis.

If you've already experienced anaphylaxis and you might encounter the triggering agent again, then healthcare providers recommend that you keep an epinephrine auto-injector on hand. It could keep you out of the hospital, or even save your life.

If you've already experienced anaphylaxis and you don't know what triggered the allergic reaction, you also need an EpiPen in case you encounter the unknown trigger again.

How are EpiPens prescribed?

Epinephrine, also known as adrenaline, is prescribed to adults as a 2-pack of prefilled pen syringes or auto-injectors. EpiPens will need to be replaced after their expiration date, when the medication begins to break down. You can find the expiration date on the medication box or on the device itself.

Is Pay-per-visit right for me?

checkmark in a teal circle
You're 18-64
checkmark in a teal circle
You aren't seeking your first EpiPen prescription
checkmark in a teal circle
You’re at risk of having a severe allergic reaction (anaphylaxis)

Commonly prescribed EpiPens

Your Amazon One Medical provider will determine which (if any) epinephrine auto-injector is medically appropriate for you based on your symptoms and health history. If you're prescribed medication, pick it up at a pharmacy of your choice. Choose Amazon Pharmacy for free delivery and transparent Prime pricing. The cost of your prescribed medication may be covered by health insurance.
EpiPen icon
Epinephrine 0.3 mg auto-injectors
• Adrenaclick
• AUVI-q (voice-guided)
• EpiPen
• EpiPen generic
• Symjepi
Online doctor smiles at telehealth patient from mobile phone

Not sure where to start?

For a one-time fee of $49, a One Medical provider can diagnose and treat common health complaints, renew prescriptions, and answer your questions in real time. Restrictions apply.

Frequently asked questions

About Amazon One Medical

What are my telehealth options for this treatment?
Amazon One Medical offers multiple ways to get care from the comfort of your own home.

If you're a One Medical member and you live in a state where One Medical has offices, you can schedule Remote Visits with One Medical providers, which are billable to you or your health insurance. As a member, you can also get 24/7 on-demand virtual care with Treat Me Now or Urgent Video Chat via the One Medical app at no extra cost, no matter where you live in the United States.

If you're not a One Medical member, you can start a one-time virtual visit with Pay-per-visit. Pay-per-visit offers two types of telehealth for Amazon customers: video visits and message-only visits. Video visits are available for $49 in all 50 states and D.C. Message-only visits are currently available for $29 in 34 states.

To see your Pay-per-visit options, first choose your state.
Can I use my health insurance for Pay-per-visit?
Amazon One Medical doesn't accept health insurance for Pay-per-visit care. You can submit a claim to your insurance provider for reimbursement, but we can’t guarantee they’ll reimburse you for your one-time virtual visit.

If you normally use insurance to pay for your medications, you can do that with medications prescribed through all Amazon One Medical services. Amazon Pharmacy accepts most insurance plans. For other pharmacies, please talk with your pharmacy directly about insurance coverage. The cost of medication isn’t included in the cost of your visit.
What happens if my provider can't diagnose or treat my health issue through Amazon One Medical Pay-per-visit?
If your provider can’t diagnose or treat your health issue through Pay-per-visit, they may recommend that you see a primary care provider or a specialist for in-person care. If that happens, you won't be charged.
How does Amazon One Medical protect my health information?
Amazon One Medical protects customers’ protected health information (PHI) with stringent, Health Insurance Portability and Accountability Act (HIPAA)-compliant privacy and security practices to keep information safe and secure.

We’re committed to building an infrastructure that fosters and promotes a culture of customer privacy and a strong commitment to safeguarding health information. We maintain administrative, physical, and technical safeguards to protect customer information. This includes conducting rigorous security reviews and testing during product development, using encryption to protect data, and providing features like two-step verification to help customers protect their accounts.

Amazon does not sell customers’ personal information, including PHI.

About EpiPens and anaphylaxis

What does an EpiPen do?
Epinephrine, the medication in an EpiPen, is the only effective treatment for anaphylaxis. After epinephrine is injected into the thigh of someone experiencing anaphylactic shock, the medication immediately starts working to reduce their symptoms.

While antihistamines can treat mild allergic reactions, there's no life-saving substitute for epinephrine when multiple organ systems are involved.
How much do EpiPens cost?
The cost of an EpiPen can vary widely depending on insurance coverage, pharmacy discounts, and whether you choose generic or brand-name medication. The U.S. Food and Drug Administration (FDA) approved generic EpiPen options in 2018, which lowered prices for many people at risk of anaphylaxis.
What can trigger anaphylaxis?
The most common triggers of anaphylaxis are medications (like antibiotics or NSAIDs), stinging insects (like bees, wasps, or fire ants), and foods (like shellfish, peanuts, or tree nuts). But in up to 20% of cases, the trigger is unknown.

Anaphylaxis can happen quickly after exposure to the allergen, normally within one to two hours, and sometimes within minutes. It can also reoccur up to 3 days after exposure in what's known as a biphasic reaction, which is why people at high risk should be monitored closely after an initial allergic reaction.

Did you know?
• Up to 51% of anaphylactic reactions happen at home
60% of U.S. adults who experience anaphylaxis don’t have epinephrine available
How do you recognize the signs of anaphylactic shock?
Someone with anaphylaxis might have a mild allergic reaction that rapidly gets worse, typically affecting their breathing. Most deaths from anaphylactic shock occur within the first hour. Multi-organ symptoms can include one or a combination of the following:
• Difficulty breathing
• Hives (skin rash with itchy bumps)
• Skin itching or flushing
• Swelling of the tongue, lips, or uvula
• Swelling or tightness in the throat
• Feeling like you have a "lump" in your throat
• Sudden persistent cough or throat clearing
• Wheezing
• Abdominal cramps or vomiting
• Incontinence
• Low blood pressure (systolic BP lower than 90 or at least 30% lower than usual)*
If you’re experiencing symptoms of anaphylactic shock, please call 911 or go to an emergency room (ER) as soon as possible.
*Low blood pressure (hypotension) can sometimes be the sole symptom of anaphylactic shock.
Clinical sources
1. Brown, J. C., Simons, E., & Rudders, S. A. (2020). Epinephrine in the Management of Anaphylaxis. The journal of allergy and clinical immunology. In practice, 8(4), 1186–1195. Retrieved from https://pubmed.ncbi.nlm.nih.gov/32276687/
2. Pflipsen, M. C., & Vega Colon, K. M. (2020). Anaphylaxis: Recognition and Management. American family physician, 102(6), 355–362. Retrieved from https://www.aafp.org/pubs/afp/issues/2020/0915/p355.html
3. Wood, R. A., Camargo, C. A., Jr, Lieberman, P., Sampson, H. A., Schwartz, L. B., Zitt, M., Collins, C., Tringale, M., Wilkinson, M., Boyle, J., & Simons, F. E. (2014). Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States. The Journal of allergy and clinical immunology, 133(2), 461–467. Retrieved from https://pubmed.ncbi.nlm.nih.gov/24144575/