Female torso hunches over with period pain, hands over pelvic area; male healthcare provider takes a woman's blood pressure measurement with BP cuff; online doctor smiles at telehealth patient from mobile phone

Period cramp relief

Suffering from menstrual cramps? Prescription medications can target the hormone-like compounds that cause period pain.
Get care from Amazon One Medical with a one-time virtual visit or become a member to easily book an in-office appointment.
Explore ways to get care


Best for
• Booking same/next-day appointments* at offices near you with the app
• Booking primary care visits* for mental health, preventive care, chronic conditions, and more in states where we have offices
• 24/7 on-demand virtual care for quick treatment of common conditions, anywhere in the U.S. at no extra cost.
• Major insurance accepted for in-office and remote visits*


Best for
• Quick treatment of common conditions
• Care by message or video**
• Self-pay visits – no insurance accepted or needed
• FSA/HSA eligible
Common conditions
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Select Rx renewal
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How to access care
One Medical app
Schedule visits, in-office or remote*
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Message with your care team
On demand
24/7 on-demand virtual care via message** and video
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Membership fee
$9/mo or $99/yr for Prime members
$199/yr for non-Prime members
No membership fee
Prime membership required
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Cost for on-demand virtual care
Included in the membership
$29 or $49
Accepted for scheduled visits
Not accepted
FSA/HSA eligible
Accepted for scheduled visits
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*These appointments will be billed to you or your insurance
**Messaging via Pay-per-visit is only available in 34 states
Learn more details via our FAQs

Get help for period pain and other health concerns




45% savings
with Prime
There’s no nearby One Medical office based on your address
But you can still access 24/7 on-demand care with the One Medical app
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Book same/next day in-office appointments via the app
Scheduled visits (in-office/remote) billed to your insurance separately (cost sharing applies). One Medical accepts most insurance.
For $9/month, you can
• Book same/next day appointments at offices near you with the One Medical app
• Get 24/7 on-demand virtual care via video or messaging
• Send and receive secure messages with your care team
• Easily request prescription refills and renewals

Quickly treat period pain with 24/7 virtual care

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*Messaging is not available in some states
• Self-pay visits - insurance not accepted or needed, FSA/HSA eligible
• Fast care - no appointment necessary
• Prime not required
• Your health data is secure and protected by our practices and by law
How it works
1. Choose a condition you need help with, answer some questions, and connect with a provider through message or video
2. Pick up any prescribed medication at a pharmacy of your choice or have it delivered
3. You have 14 days to follow up with the provider on any questions you may have
Amazon Clinic is now Amazon One Medical
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How do period pain relievers work?

Period pain relievers generally target prostaglandins, compounds in the body that tell the uterus when to start contracting. Lower prostaglandin levels can lead to fewer period cramps.

Prescription nonsteroidal anti-inflammatory drugs (NSAIDs) can bind to enzymes involved in prostaglandin synthesis. By inhibiting this enzyme activity, these drugs can reduce period pain levels.

Is Pay-per-visit right for me?

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You're 18-55
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You experience pelvic pain that corresponds to a regular period cycle
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You've had a pelvic exam since the first time you experienced cramps
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You're not pregnant or nursing

Commonly prescribed period cramp medications

Your Amazon One Medical provider will determine which (if any) period pain treatment is medically appropriate for you based on your symptoms and health history. If you're prescribed medication, pick it up at a pharmacy of your choice. Choose Amazon Pharmacy for free delivery and transparent Prime pricing. The cost of your prescribed medication may be covered by health insurance.
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Prescription NSAIDs
Specialized NSAIDs called fenamates help relieve period pain by blocking prostaglandin action. They can be more effective for treating menstrual cramps than an over-the-counter NSAID like ibuprofen (Advil), which is derived from phenylpropionic acid.
• Diclofenac (Cataflam, Lofena)
• Mefenamic acid
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Hormonal contraceptives
Hormonal contraceptives like birth control pills can lower prostaglandin levels, leading to less menstrual pain.
• Birth control pills
• Hormonal patches
• Vaginal rings

More care for women's health

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Birth control

Amazon One Medical makes it easy to get your annual prescription.
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Urinary tract infections cause painful and frequent urination.
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Vaginal yeast infections

Prescription antifungal meds can relieve itchiness.
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Not sure where to start?

For a one-time fee of $49, a One Medical provider can diagnose and treat common health complaints, renew prescriptions, and answer your questions in real time. Restrictions apply.

Frequently asked questions

About Amazon One Medical

What are my telehealth options for this condition?
Amazon One Medical offers multiple ways to get care from the comfort of your own home.

If you're a One Medical member and you live in a state where One Medical has offices, you can schedule Remote Visits with One Medical providers, which are billable to you or your health insurance. As a member, you can also get 24/7 on-demand virtual care with Treat Me Now or Urgent Video Chat via the One Medical app at no extra cost, no matter where you live in the United States.

If you're not a One Medical member, you can start a one-time virtual visit with Pay-per-visit. Pay-per-visit offers two types of telehealth for Amazon customers: video visits and message-only visits. Video visits are available for $49 in all 50 states and D.C. Message-only visits are currently available for $29 in 34 states.

To see your Pay-per-visit options, first choose your state.
Can I use my health insurance for Pay-per-visit?
Amazon One Medical doesn't accept health insurance for Pay-per-visit care. You can submit a claim to your insurance provider for reimbursement, but we can’t guarantee they’ll reimburse you for your one-time virtual visit.

If you normally use insurance to pay for your medications, you can do that with medications prescribed through all Amazon One Medical services. Amazon Pharmacy accepts most insurance plans. For other pharmacies, please talk with your pharmacy directly about insurance coverage. The cost of medication isn’t included in the cost of your visit.
What happens if my provider can't diagnose or treat my health issue through Amazon One Medical Pay-per-visit?
If your provider can’t diagnose or treat your health issue through Pay-per-visit, they may recommend that you see a primary care provider or a specialist for in-person care. If that happens, you won't be charged.
Can I get a doctor's note through Pay-per-visit?
No. At this time, providers don't offer doctors' notes through Amazon One Medical Pay-per-visit.
How does Amazon One Medical protect my health information?
Amazon One Medical protects customers’ protected health information (PHI) with stringent, Health Insurance Portability and Accountability Act (HIPAA)-compliant privacy and security practices to keep information safe and secure.

We’re committed to building an infrastructure that fosters and promotes a culture of customer privacy and a strong commitment to safeguarding health information. We maintain administrative, physical, and technical safeguards to protect customer information. This includes conducting rigorous security reviews and testing during product development, using encryption to protect data, and providing features like two-step verification to help customers protect their accounts.

Amazon does not sell customers’ personal information, including PHI.

About period pain

What causes menstrual cramps?
Menstrual cramps are caused by painful contractions of the uterus. These contractions result in the release of the uterine lining once a month (a period). The uterus knows when it's time to start contracting when it gets a signal from prostaglandins.

Prostaglandins are compounds that function like hormones in the body. Studies show that higher prostaglandin levels can lead to more uterine cramps, higher uterine pressure, and more pain, while lower prostaglandin levels can lead to fewer uterine cramps, lower uterine pressure, and less pain.

Did you know?
• Up to 91% of young women experience period pain
29% of those women describe their pain as severe
• Only 11% of young women seek medical advice about their menstrual cramps
Are there any natural treatments for period pain relief?
Research has shown some benefits of exercise, applied heat (heating pads or hot water bottles), acupuncture, acupressure, and transcutaneous electrical nerve stimulation (TENS) on period pain.
When should I be worried about pelvic pain?
When pelvic pain is caused solely by a menstrual cycle, it's called primary dysmenorrhea (painful menstruation). When pelvic pain has another underlying cause, like endometriosis or uterine fibroids, it's called secondary dysmenorrhea.

Primary dysmenorrhea
• Pain cycles may begin 6 to 12 months after getting your first menstrual period
• Pain may start 2 to 3 days before you get your period or when you start bleeding
• Pain may last 8 to 72 hours
• Pain may decrease as you get older
Secondary dysmenorrhea
• Pain may be unusually severe and worse with time
• Pain may last longer than 2 to 3 days
• Pain may start later in life (like after age 25)
A telehealth provider will likely recommend that you see an in-person provider, likely for a pelvic exam, if you haven't experienced period pain relief after 3 to 6 months of NSAID or hormonal contraceptive treatment.

An online doctor is also likely to recommend that you see an in-person provider if you have other symptoms of secondary dysmenorrhea, like pain during sex, pelvic pain that isn't related to your menstrual cycle, or abnormal bleeding.
Can I get period pain treatment through Pay-per-visit if I have endometriosis?
Symptoms of endometriosis, a chronic condition that affects 1 in 10 women of reproductive age, can be treated with many of the same therapies that treat period cramps. If you've already been diagnosed with endometriosis, you can seek relief from your symptoms through Amazon One Medical Pay-per-visit.

Endometriosis is caused by endometrium cells growing and forming lesions outside the uterus (ectopically). The condition can cause inflammation, intense pain, and sometimes infertility. If you have signs of secondary dysmenorrhea (see FAQ "When should I be worried about pelvic pain?"), then you'll need to see a primary care provider to rule out endometriosis.

Endometriosis can be diagnosed with medical imaging (ultrasound or MRI) or a surgical biopsy, yet it often takes years (10 on average) for women to be accurately diagnosed.
Clinical sources
1. Armour, M., Parry, K., Al-Dabbas, M. A., Curry, C., Holmes, K., MacMillan, F., Ferfolja, T., & Smith, C. A. (2019). Self-care strategies and sources of knowledge on menstruation in 12,526 young women with dysmenorrhea: A systematic review and meta-analysis. PloS one, 14(7), e0220103. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655766/
2. Armour, M., Parry, K., Manohar, N., Holmes, K., Ferfolja, T., Curry, C., MacMillan, F., & Smith, C. A. (2019). The Prevalence and Academic Impact of Dysmenorrhea in 21,573 Young Women: A Systematic Review and Meta-Analysis. Journal of women's health (2002), 28(8), 1161–1171. Retrieved from https://www.liebertpub.com/doi/10.1089/jwh.2018.7615
3. Ju, H., Jones, M., & Mishra, G. (2014). The prevalence and risk factors of dysmenorrhea. Epidemiologic reviews, 36, 104–113. Retrieved from https://academic.oup.com/epirev/article/36/1/104/566554