Over-the-counter motion sickness medications like dimenhydrinate (Dramamine) and meclizine (Antivert, Bonine, Dramamine Less Drowsy) are oral antihistamines that you take 30 to 60 minutes before travel. You can take them every 8 hours.
Scopolamine (Transderm-Scop) is a prescription adhesive patch that's FDA-approved to treat the nausea and vomiting associated with motion sickness. You apply the anti-nausea patch behind your ear 4 to 12 hours before travel and change it every 72 hours as needed.






