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A hand holds a blue prep hiv prevention pill

PrEP (HIV pre-exposure prophylaxis)

Same/next-day office appointments, complemented by 24/7 virtual care

$99

/year
Up to
50% savings
with Prime
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This benefit is exclusively for Prime members
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How One Medical Works

Schedule in-office or remote visits for chronic care (billed to you or your insurance)
Easily access your health records and care plan

Get more as a member

Start new chats with your care team, anytime, anywhere in the U.S.
Easily request new prescriptions and renewals
Get 24/7 on-demand video chat or messaging for urgent needs*
*Your provider may recommend scheduling in-office or remote visits for further diagnosis or ongoing care. These aren't included in membership and are billed to you or your insurance (copays/deductibles may apply). Available where One Medical operates.
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Your account has an Amazon One Medical Membership

On-demand care for this condition is included with membership

With your membership, you can:

Get 24/7 on-demand care via Video Chat or Treat Me Now
Convenient prescription refill and renewal requests
View a summary and action items after your visit, and directly message your care team
Go to One Medical
We don't have in-office providers near 37217
You can still use all of our virtual services in this location. If you're traveling, you can also visit any of our 200+ locations nationwide.

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preventive care

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Same / next-day appointments
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One Medical accepts insurance

In-office and scheduled remote visits are best for ongoing care with a primary care provider, and are billed to you or your insurance (deductibles and copays apply, depending on your insurance plan).
See accepted insurance plans

What to expect from Amazon One Medical

Work with your primary care provider to find the best care plan — whether you're starting PrEP or looking for ongoing support, they can help connect you to the right care and resources
2 minute average lobby wait time
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What is PrEP?

HIV PrEP is medication taken to prevent getting HIV. PrEP prevents the HIV virus by blocking its ability to make copies of itself. It’s recommended for people who are at risk of being exposed to HIV through sex or injection drug use.

How effective is PrEP at preventing HIV?

When taken correctly, PrEP lowers the risk of getting HIV through sex by about 99% and lowers the risk of getting HIV through injection drug use by at least 74%.
But it’s important to know that there’s still a small chance of getting HIV even if you take PrEP exactly according to directions. Using condoms every time you have sex and not sharing needles will reduce your HIV risk even further, and these steps will also help to prevent other infections that PrEP doesn’t protect against.

Oral and injectable PrEP treatments (antiretrovirals)

Injectable medication icon
Injectable PrEP therapy
• Long-acting cabotegravir (Apretude)
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PrEP HIV prevention pills
• Tenofovir disoproxil fumarate (TDF) and emtricitabine (Truvada)
• Tenofovir alafenamide (TAF) and emtricitabine (Descovy)

Related conditions that One Medical treats

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STI testing & treatment

Get sexual health screening ›
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Genital herpes

Get genital herpes treatment ›
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Genital warts (HPV)

Get genital warts (HPV) treatment ›

Frequently asked questions

About Amazon One Medical

Where are scheduled visits available? Is there a One Medical office near me?
In-Office Visits are scheduled appointments with the provider of your choice. Remote Visits are scheduled, virtual appointments with the provider of your choice and are available in U.S. states where One Medical offices are located.
One Medical currently has primary care doctors' offices in or around the following locations:
•
Atlanta, GA
•
Austin, TX
•
Boston, MA
•
Chicago, IL
•
Columbus, OH
•
Connecticut
•
Dallas-Ft. Worth, TX
•
Los Angeles, CA
•
Miami-Ft. Lauderdale, FL
•
New Jersey
•
New York
•
Orange County, CA
•
Phoenix, AZ
•
Portland, OR
•
Raleigh-Durham, NC
•
San Diego, CA
•
Seattle-Tacoma, WA
•
San Francisco Bay Area, CA
•
Washington D.C. Metro Area (DMV) and Northern Virginia
In-Office and Remote Visits are not included in membership and are billed to you/your insurance; copays and deductibles may apply.
Find out more about One Medical locations, including One Medical Seniors offices, on the location page.

About PrEP

How often do I need to take PrEP?
Most people on PrEP take a pill by mouth once a day, but an on-demand approach to HIV prevention (PrEP 2-1-1) may be an option for some people who were assigned male at birth and can plan ahead for sex. PrEP 2-1-1 involves taking two pills 2 to 24 hours before having sex and one pill 24 hours after sex.
Most people on PrEP take a pill by mouth once a day, but an on-demand approach to HIV prevention (PrEP 2-1-1) may be an option for some people who were assigned male at birth and can plan ahead for sex. PrEP 2-1-1 involves taking two pills 2 to 24 hours before having sex and one pill 24 hours after sex.
People who can’t take other PrEP medications or would have trouble taking a pill every day may be eligible for an injectable PrEP medication that’s given every other month - cabotegravir LA. This therapy is more expensive, may not be covered by insurance, and requires more visits to a healthcare provider.
Your provider will partner with you to determine which (if any) PrEP medication is ideal for you based on your risk for getting HIV, your health history, your preferences, and your insurance coverage.
How often do I need to follow up while taking PrEP?
Regular lab work and follow-up visits are an important part of taking PrEP. Your provider will order routine lab work for two reasons: to be sure that you’re still HIV-negative and to monitor for medication side effects. Your provider will likely ask you to come in for HIV testing every 3 months and may suggest testing for other STIs at the same time, if you’re at risk. Your provider will also check your kidney function once or twice a year if you’re taking an oral pill for PrEP.
Does PrEP work right away?
If you’re starting PrEP medication or restarting PrEP after a break, it will take some time for your body to build up enough of the drug to prevent HIV effectively. For receptive anal sex (bottoming), daily PrEP pills reach maximum protection from HIV after about 7 days. It takes around 21 days after starting PrEP pills to reach maximum protection for receptive vaginal sex and injection drug.
It’s less clear how long it takes to be maximally protected when taking injectable PrEP medication, but it’s safest to avoid situations that would put you at higher risk for getting HIV for at least a week and up to a month after starting injectable medication.
Are PrEP medications safe to use long-term?
PrEP medications are safe and pose far fewer health risks than HIV infection. Your provider will likely recommend that you continue PrEP for as long as you’re at increased risk of getting HIV. If your risk changes or you need to stop PrEP for another reason, talk with your provider about the best timing and any special precautions you should take rather than stopping medication on your own.
Do PrEP medications cause side effects?
PrEP medication causes few or no side effects for most people. A small percentage of people who take an oral pill for PrEP notice side effects like headache, nausea, or abdominal pain during the first few weeks after starting PrEP, but these side effects typically go away with time. People taking injectable PrEP medication may notice diarrhea, headache, fever, fatigue, difficulty sleeping, nausea, or dizziness when first getting started.
Does PrEP prevent STIs other than HIV?
PrEP medications don’t prevent STIs other than HIV. To protect against other STIs, use a condom every time you have sex, and consider talking with your provider to find out whether other prevention strategies like doxyPEP would be right for you.
What are the symptoms of HIV infection?
If you’re at risk of getting HIV, it’s important to know which signs and symptoms to watch out for. An early HIV infection can cause symptoms that might feel similar to a cold, flu, or COVID-19:
• Fever
• Chills
• Body aches or joint pain
• Headache
• Sore throat
• Swollen lymph nodes
• Fatigue
• Rash
These symptoms may show up several weeks after becoming infected and will go away on their own, even though HIV remains active in the body. Lab testing is the best way to know whether symptoms are due to an early HIV infection or something else.
Clinical sources
1. Anderson, P. L., Glidden, D. V., Liu, A., Buchbinder, S., Lama, J. R., Guanira, J. V., McMahan, V., Bushman, L. R., Casapía, M., Montoya-Herrera, O., Veloso, V. G., Mayer, K. H., Chariyalertsak, S., Schechter, M., Bekker, L. G., Kallás, E. G., Grant, R. M., & iPrEx Study Team (2012). Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Science translational medicine, 4(151), 151ra125.
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