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Woman touches a clogged pore pimple on her cheek

Acne treatment

Share your symptoms with Health AI and get treatment from a provider if appropriate.

How it works

Check-in with Health AI
Complete a check-in with the help of Health AI.
Discuss with a provider
Review your health concern or treatment request with a One Medical provider via message.
Get treatment
Receive your care plan. If appropriate, prescriptions are sent to your pharmacy and, if you use Amazon Pharmacy, delivered to your door (if eligible).
Smiling One Medical provider delivers telehealth care

Common acne treatments

Your Amazon One Medical provider will determine which (if any) acne treatment is medically appropriate for you based on your symptoms and health history. If you're prescribed medication, your provider will send the prescription to your preferred pharmacy. Choose Amazon Pharmacy for free delivery and transparent Prime pricing. The cost of your prescribed medication is not included with the treatment cost and may be covered by health insurance.
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Topical retinoids

• Tretinoin (Retin-A) cream
• Adapalene (Differin) gel
• Tazarotene (Avage, Tazorac)
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Topical antibiotics

• Clindamycin (Cleocin)
• Erythromycin (A/T/S, EMGEL, Erygel)
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Oral antibiotics

• Doxycycline
• Minocycline
• Tetracycline
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Benzoyl peroxide

Topical antiseptic available in many forms and in combinations like benzoyl peroxide-clindamycin (BenzaClin Gel, Acanya, Neuac) and benzoyl peroxide-adapalene (Epiduo)
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Salicylic acid and azelaic acid

Skin exfoliants available in over-the-counter and prescription strength
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Hormonal agents

To treat hormonal acne in women, providers may prescribe spironolactone (Aldactone) or combined oral contraceptives
Bearded man smiles into a mirror while applying acne cream to his face

What is acne?

Common acne (acne vulgaris) is a chronic skin condition that causes inflammation on areas of the body like the face, back, and chest. Why there? Because these areas tend to be rich in oil glands that can clog your pores (hair follicles), causing pimples.

Why do I get acne?

Acne can be caused by hormones, genetics, the amount of oil your skin naturally produces, and other underlying factors that are largely out of your control. Fortunately, the condition is very treatable.
The best acne treatment is the one that works for your skin type and addresses underlying causes. Healthcare providers often prescribe a combination of acne medications for the best results.

Frequently asked questions

See all Amazon One Medical FAQs
Acne vs. pimples: What's the difference?
A pimple is a general term for a clogged hair follicle (pore), which is also known as a comedone. There are a few different types of pimple, and they don't all mean you have acne:
• Blackheads: small, inflamed bumps with a black tip, also known as open comedones
• Whiteheads/pustules: small, inflamed bumps with a pus-filled tip, also known as closed comedones
• Papules: small, inflamed bumps that don't have a pus-filled tip
• Nodules: large (5mm+), inflamed lesions that are deeper than papules or pustules
• Cysts: a more severe form of nodule that often leads to acne scars
What can I do to improve my self-esteem while getting acne treatment?
It may take time to find the right combination of acne medications for your skin, but while you're waiting for these clinically-proven acne treatments to work, you can remind yourself of the following:
• Acne isn't your fault. It doesn't mean that you're unclean or unhealthy. Acne is a chronic skin condition that's largely inherited. If your parents had acne, you're more likely to have acne.
• Acne affects all ages, not just teens. And it's the #1 reason that Americans visit the dermatologist. You are not alone.
If you're struggling emotionally as you and your provider evaluate the best acne medications for your unique skin profile, don't hesitate to reach out to a mental health counselor or a therapist. It's normal for heightened self-consciousness to lead to feelings of depression or social anxiety. A therapist can help you build strategies to work through your distress.
Can I get a prescription for isotretinoin (Accutane) through Amazon One Medical On-Demand Care?
No. We recommend seeing a primary care provider for guidance on taking isotretinoin (Accutane). Prescriptions for this medication may require lab testing and follow-up care.
If you have severe acne that hasn't responded to the most aggressive treatments, virtual care isn't the most appropriate treatment pathway for you.
Can I get a prescription for clascaterone (Winlevi) through Amazon One Medical On-Demand Care?
No. Clascoterone (Winlevi) can sometimes help with acne, but it’s often very costly and usually not covered by insurance. On-Demand Care providers don't prescribe Winlevi, even if you plan to pay for it yourself.
Because Winlevi is best managed by a dermatologist, we recommend seeing a dermatologist if you’re interested in starting or continuing this medication.
Can I get a prescription for tretinoin (Retin-A) even if I don't have acne?
Tretinoin is a common acne treatment that's also FDA-approved for treating the signs of aging. If you're most concerned about sun spots, general skin firmness or texture, or fine lines and wrinkles, this isn't the most appropriate type of treatment for you. We recommend that you request treatment for anti-aging skin care.
Can I get treatment for hidradenitis suppurativa (HS) through On-Demand Care?
No. If you have hidradenitis suppurativa (HS), a chronic inflammatory skin condition characterized by painful lesions in areas where the skin rubs together, we recommend that you see a primary care provider for in-person care.
Clinical sources
1. Heng, A. H. S., & Chew, F. T. (2020). Systematic review of the epidemiology of acne vulgaris. Scientific reports, 10(1), 5754.
2. Oge', L. K., Broussard, A., & Marshall, M. D. (2019). Acne Vulgaris: Diagnosis and Treatment. American family physician, 100(8), 475–484.
3. Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., Bowe, W. P., Graber, E. M., Harper, J. C., Kang, S., Keri, J. E., Leyden, J. J., Reynolds, R. V., Silverberg, N. B., Stein Gold, L. F., Tollefson, M. M., Weiss, J. S., Dolan, N. C., Sagan, A. A., Stern, M., … Bhushan, R. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945–73.e33.
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