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Tube of vaginal estrogen cream for menopause symptom of vaginal dryness

Vaginal dryness treatment

Share your symptoms with Health AI and get treatment from a provider if appropriate.

How it works

Check-in with Health AI
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Discuss with a provider
Review your health concern or treatment request with a One Medical provider via message.
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Receive your care plan. If appropriate, prescriptions are sent to your pharmacy and, if you use Amazon Pharmacy, delivered to your door (if eligible).
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Common vaginal dryness treatments

Your Amazon One Medical provider will determine which (if any) vaginal dryness treatment is medically appropriate for you based on your symptoms and health history. If you're prescribed medication, your provider will send the prescription to your preferred pharmacy. Choose Amazon Pharmacy for free delivery and transparent Prime pricing. The cost of your prescribed medication is not included with the treatment cost and may be covered by health insurance.
Oral estrogen prescriptions for menopause symptoms aren't available through On-Demand Care.
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Vaginal estrogen therapy

Low-dose estrogen treatments can increase vaginal secretions, restore normal vaginal pH and microflora, and strengthen vaginal tissue. These prescription medications can also have urinary tract benefits.
• Conjugated estrogen (Premarin) intravaginal cream
• Estradiol (Estrace) intravaginal cream
• Estradiol (Estring, Femring) vaginal ring
• Estradiol (Vagifem, Yuvafem) vaginal tablet
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Vaginal lubricants

OTC lubricants can be used during sex to reduce friction and ease discomfort.
• Water-based (Astroglide, Slippery Stuff, K-Y Jelly)
• Silicone-based (Pjur, ID Millennium)
• Oil-based (Elegance Women's Lubricant, Simply Slick)
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Vaginal moisturizers

OTC vaginal moisturizers, often bioadhesive gels or inserts, can be used regularly. Their benefits typically last 2 to 3 days.
• Feminease
• Hyalo GYN
• K-Y Liquibeads
• Moist Again
• Replens
• Revaree
• Vagisil Moisturizer
Female healthcare provider discusses vaginal dryness symptoms with female patient in doctor's office

What’s the difference between over-the-counter (OTC) and prescription vaginal dryness medications?

OTC vaginal lubricants and moisturizers can treat mild symptoms of vaginal dryness. They can enhance comfort during sex and increase vaginal moisture, but they won't reverse vaginal atrophy.
Prescription vaginal dryness treatments often contain estrogen, which can actually strengthen vaginal tissue.

Frequently asked questions

See all Amazon One Medical FAQs
What causes vaginal dryness (vaginal atrophy)?
Vaginal dryness is caused by a decline in estrogen levels in the blood. Estrogens (the "female" sex hormones) influence hundreds of functions in the body, including the menstrual cycle. These hormones also help maintain the tissue strength of the vagina, labia, clitoris, vulva, urethra, and bladder.
Between premenopause and postmenopause, women experience a 95% reduction in their estradiol estrogen levels.
When estrogen levels decline, usually due to menopause, women can have the following symptoms:
• Less vaginal lubrication
• Thinning of vaginal tissue due to reduced collagen production
• Loss of vaginal elasticity
• Increased vaginal pH
• Loss of pubic hair
Collectively, these symptoms make up a condition that healthcare providers call vaginal atrophy, vulvovaginal atrophy, atrophic vaginitis, or—since 2014—the genitourinary syndrome of menopause (GSM).
GSM can lead to discomfort, pain, sexual impairment, and distress. Research suggests that this treatable condition affects up to 85% of women over age 40.
Did you know?
• Vaginal dryness affects 60% of women after menopause
• Up to 70% of women with vaginal atrophy don’t discuss their symptoms with a healthcare provider
What are the symptoms of vaginal atrophy?
Vaginal atrophy, now called genitourinary syndrome of menopause (GSM), comprises far more than just vaginal dryness. GSM can have a wide range of symptoms, including the following:
• Vaginal burning, irritation, or itching
• Milky or yellow vaginal discharge
• Inflammation (swollen vulva or labia)
• Dryness during daily activities
• Dryness during sex
• Pain or discomfort during sex
• Sensitive vaginal tissue sometimes leading to small tears (fissures)
• Loss of vaginal elasticity (tightness)
• Recurring urinary tract infections (UTIs)
• Urinary urgency
• Pain or burning when urinating
• Levator spasm (sporadic pain in your rectum)
These symptoms can occur at the same time as other common menopause symptoms like hot flashes.
Can I experience vaginal atrophy even if I'm not going through menopause?
Menopause isn't the only cause of vaginal atrophy. Other possible reasons for low estrogen levels include the following:
• Childbirth (vaginal dryness postpartum)
• Breastfeeding
• Hypothalamus issues that lead to a period stopping (amenorrhea)
• Antiestrogenic medication
• Pelvic radiation
• Surgical removal of the ovaries
• Breast cancer
The median age of menopause is 51.4 years, but younger women can also experience the change. When someone 40 to 50 goes through menopause, it's called early menopause. When someone younger than 40 experiences it, it's called primary ovarian insufficiency.
How can I increase my natural lubrication?
There are no clinically-proven natural remedies for vaginal dryness that will increase estrogen levels in the body. But research shows that having sex can help preserve vaginal tissue, probably by increasing blood flow to the area.
Clinical sources
1. Bachmann, G., & Pinkerton, J. (2022). Genitourinary syndrome of menopause (vulvovaginal atrophy): Clinical manifestations and diagnosis. In A. Chakrabarti (Ed.), UpToDate. Accessed April 20, 2023, from https://www.uptodate.com/contents/genitourinary-syndrome-of-menopause-vulvovaginal-atrophy-clinical-manifestations-and-diagnosis
2. Goncharenko, V., Bubnov, R., Polivka, J., Jr, Zubor, P., Biringer, K., Bielik, T., Kuhn, W., & Golubnitschaja, O. (2019). Vaginal dryness: individualised patient profiles, risks and mitigating measures. The EPMA journal, 10(1), 73–79.
3. Sarmento, A. C. A., Costa, A. P. F., Vieira-Baptista, P., Giraldo, P. C., Eleutério, J., Jr, & Gonçalves, A. K. (2021). Genitourinary Syndrome of Menopause: Epidemiology, Physiopathology, Clinical Manifestation and Diagnostic. Frontiers in reproductive health, 3, 779398.
4. Tomczyk, K., Chmaj-Wierzchowska, K., Wszołek, K., & Wilczak, M. (2023). New Possibilities for Hormonal Vaginal Treatment in Menopausal Women. Journal of clinical medicine, 12(14), 4740.
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