COVID-19 treatment

Question 1

Can I get a COVID-19 test through On-Demand Care?

Answer

No. COVID-19 testing isn't available through Amazon One Medical On-Demand Care. If you think you have COVID-19, it's important to test as soon as possible. Paxlovid treatment requires a positive test result or a confirmed exposure and the medication needs to be prescribed within 5 days of symptoms starting.

Your telehealth provider will accept positive test results from a rapid home test or a molecular (PCR) test. You can get a rapid, at-home COVID-19 test at brick-and-mortar pharmacies and grocery stores, or order one through any online service that offers same-day delivery.

Question 2

Who can take Paxlovid?

Answer

The FDA has authorized the emergency use of nirmatrelvir-ritonavir (Paxlovid) for people who aren't seriously ill with COVID-19, but who have a higher risk of becoming seriously ill from the virus. The CDC identifies numerous risk factors that make someone eligible for Paxlovid treatment, including the following:

• Age 65 or over (if you're vaccinated against COVID-19)

• Age 50 or over (if you're not vaccinated against COVID-19)

• BMI 30 or higher (obesity)

• Physical inactivity (sedentary lifestyle)

• Current use or former regular use of tobacco products

• Pregnancy or recent pregnancy (in the last 6 weeks)

You may also qualify for treatment if you have an underlying health condition, including one of the following:

• Asthma

• Cancer, HIV, or a weakened immune system

• Chronic kidney disease (with eGFR above 30mL/min)

• Chronic liver disease

• Cystic fibrosis

• Parkinson’s disease or dementia

• Diabetes

• Disability that makes it difficult to do certain activities or interact with the world around you, including Down syndrome, ADHD, autism, and physical disabilities

• Heart condition like heart failure, coronary artery disease (CAD), or arrhythmia (irregular heartbeat)

• Mental health condition like depression or schizophrenia

• Sickle cell disease or thalassemia

• History of stroke, TIA, or cerebrovascular disease

• Substance use disorder (drugs or alcohol)

• Tuberculosis

Question 3

What if I can't take Paxlovid?

Answer

In cases where a patient can't safely take Paxlovid, a provider may prescribe molnupiravir (Lagevrio), an alternative COVID-19 treatment.

Question 4

Is it safe to take Paxlovid with my other medications?

Answer

Paxlovid is an antiviral medication that can interact with many different types of prescription drugs and over-the-counter supplements, including the following:

• Antidepressants like buproprion (Wellbutrin) and trazodone

• Antiviral medications that treat HIV

• Asthma inhaler with salmeterol

• Birth control*

• Blood thinners like warfarin (Coumadin) or rivaroxaban (Xarelto)

• Cholesterol medications like atorvastatin (Lipitor) or simvastatin (Zocor, FloLipid)

• Erectile dysfunction (ED) medications like sildenafil (Viagra)

• Heart or blood pressure medications

• Migraine medications like ergotamine

• Seizure medications like carbamezapine or phenytoin

• St. John's wort

Your Amazon One Medical provider will review your health information and let you know if you'll need to pause or adjust other therapies before you take Paxlovid.

*Paxlovid may affect how well birth control pills work. If you take hormonal birth control pills, your provider may recommend using an additional barrier method (like a condom) until after you complete a full menstrual cycle following the 5 days of Paxlovid treatment.

Question 5

Clinical sources

Answer

1. CDC. (2020, February 11). Healthcare Workers. Centers for Disease Control and Prevention. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/outpatient-treatment-overview.html

2. Pfizer. (2023). Paxlovid: Highlights of prescribing information. labeling.pfizer.com/ShowLabeling.aspx?id=19599

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COVID-19 treatment

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Paxlovid

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